You constrain the target such that the target automatically misses with all attacks made against creatures that are not of the opposite alignment of it. For example, a lawful evil target would automatically fail at all attacks except those made against chaotic good creatures, and a neutral good target would automatically fail at all attacks except those made against neutral evil creatures. For the purposes of _antithetical constraint_, creatures that are chaotic evil, chaotic good, lawful evil, or lawful good are all considered to have the opposite alignment of a target whose alignment is neutral with no other alignment components. This restriction doesn’t apply to effects that do not require attack rolls, such as [_magic missile_](/spells/magic-missile).